Hi there,
This is a special requirement and not something like a generic requirement. Yes, this is quite possible. You can refer to the following url for the idea as how to achieve the same.
http://www.amitsgarage.com/knowledge-base/grocerycrud/take-control-of-the-add-edit-page/
You will have to take in some prominent steps like pushing in the actual values that you have with u currently to a controller / method, there - it will pull in the fresh set of values and compare with the current values (that you have) .. based on the same you can build a json indicating changes. When returned back, you can take in necessary actions / steps as required.
Remember 1 thing - the above solution shared looks at handling event based on changes for specific field. But in your case - the same can be switched to some timeout function that will keep making ajax calls.
Hope this clears your query / criteria.
Happy GCing :)